KMID : 0043319860090010026
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Archives of Pharmacal Research 1986 Volume.9 No. 1 p.26 ~ p.28
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Synthesis of Certain Thiaxanthones as Potential Schistosomicidal Agents
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El-Kerdawy MM
El-Emam/El-Subbagh
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Abstract
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Twenty nine substituted thiaxanthone derivatives were synthesized for schistosomicidal evaluation. The compounds, 1-morpholino-4-methyl-6-nitrothiaxanthone and 1-(2-diethyl-aminoethylamino)-4-methyl-6-nitrothiaxanthone dipicrate were found to possess promising schistosomicidal activity against Schistosoma mansoni in mice.
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